Depopulate rhymes with:
populate, copulate, populate, copulate, manipulate, populate, stipulate, accumulate, articulate, calculate, circulate, coagulate, copulate, emulate, formulate, innoculate, inoculate, manipulate, miscalculate, overregulate, populate, recalculate, reformulate, regulate, reregulate, speculate, stimulate, stipulate, strangulate, tabulate
Depopulate sounds like:
dabbled, dapolito, davault, deadbolt, debilitate, debilitated, debility, debold, debolt, default, defaulted, deflate, deflated, defollet, deplete, depleted, deployed, devaluate, devaluated, devalued, devault, devilwood, dibbled, diebold, dippold, dippolito, doubled, doubleday, dufault, duffield